Lindsay Orr was active and healthy, marathons and walking around the whole Colorado. During pregnancy, he, the leading cause of preechampsis, the leading cause of Preterm Birth, the leading cause of mother’s death and the disease, a dangerous headache and dangerous high blood pressure signs. 32 weeks off to save him and her baby’s life.
Now, two years later, he continues his long-term effects of Peeklampsia, because Lindsay also developed a situation without chronic high blood pressure, never before pregnancy.
Pregnancy complications are dangerous for the mother and baby, such as Prelampsia, early childbirth and fetal growth restriction. These complications can hit without aware of pregnancies to be sent to the crisis. For women who do not have risk factors for complications such as Lindsay and Preeclampsia, experience, experience and surreal is the most joyful time of a parent’s life.
So many women, families and doctors are unacceptable for so many women is left behind Every major industrial nation in the presence of motherhood health crisis. This is heartwarming 20% of pregnant women Live the crisis of pregnancy complication. This creates long-term physical and mental health effects for women, as well as affect children’s health results.
A prenatal model made 100 years ago
For investment midwife and pregnancy health, the Prenatal Care Model The Prenatal Care for Maternal Health has remained unchanged in the last 100 years. Again the rates of complications Preeclampsia continues to rise and defective childbirth It is the highest level in the United States, we need to understand what happens in pregnancy to reverse these trends.
Unless biological approaches, OB / Gyns and care teams have to trust generalized properties and demographics. These include trying to determine who can be at age, BMI, race and socio-economic status, for pregnancy complications. This US preventative services TaskForce The instructions identify them as average risk factors.
Unfortunately, 80% of pregnancies At least one of these moderate risk factors makes it a weak indicator of those who are really at high risk for prime. Not surprisingly, patients, clinicians and care teams, preechlampsiers are led to less in places where to create an individual care plan to reduce the risk of preechlamps. Those who do not have some risk factors have normal, non-argument pregnancies by developing the severe forms of preeklamps and most average risk factors.
The status quo does not work. Women deserve better. Moms deserve better. Families deserve better. We must understand women’s biology and pregnancy journey, if we want to prevent, treat and manage, treat and manage diseases that affect women.
A new period of pregnancy health
For moms and babies, they need scientific progress to better understand what happened in pregnancy so that we can avoid complications and early childbirth crises before taking place. Of course, this idea is not new. Five-year survival rates After the scientific concept of molecular drivers of breast cancer for breast cancer, we went to about 90% of breast cancer.
Mirvie’s foundation, the first type learn Complete the concepts we never know about pregnancy. We have investigated about 11,000 different pregnancy biology from women in the United States and gather thousands of RNA transcripts and hundreds of clinical details from each patient and become millions of diet. Using this rich database combined with advanced machine learning, Mirvie Preeclampsia has identified unique molecular signatures to predict the risk of early childbirth and severe fetal growth.
What does this mean for clinicians? Doctors and care teams can move away from generalized risk factors and move towards an individual care approach managed by an accurate understanding of the disease. Clinicians and care teams can create better results for the mother and baby, by determining care plans and monitoring methods for the right patients at the right time.
Personalized medicine is a standard of care in areas such as oncology and cardiology. For complications based on biology, which pregnancy is really high risk, can be able to understand women pre-plan and help them do everything possible Proof-based strategies Aspirin adopting daily aspirin, watching blood pressure regularly and enter lifestyle changes as diet and exercise. Then we can prevent the disease, deaths, long nicu and prevent trauma.
With this type of information, we can guide individual patient care and accurate medicine by developing new, target treatments in the future. At a molecular level, we are closer to understand how the most risky for pregnancy and how biology affects the highest risk. In the 1990s, similar to breast cancer can move in the direction of a new standard of care based on biology, tailoring and treatment based on molecular features of any pregnancy.
I hope that finally we can finally use a new care and reverse course in the motherhood health crisis, to predict the risk of complications such as preeclampsia.
It is the Director General of Obstacle Jain Cofounter and MIRVIE.
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