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Self-enhanced ultrasonic cutting technology and fully automatic generation sequence library construction system, “Qingyuan Kaiwu” helps to change the internal sequence equipment. Early projects

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Self-enhanced ultrasonic cutting technology and fully automatic generation sequence library construction system, “Qingyuan Kaiwu” helps to change the internal sequence equipment. Early projects


Longing, the way of catalysis of the new crown epidemic in the last two years, the path of life has become a warm place in the primary market, but with the emergence of homogeneous competition, the “intra-roll” trend was gradually discovered. In this context, how should beginners deal with market competition?

Recently, the Global Health Industrial Development Research Institute and the Global Health Industry Innovation Center (GHIK), the global health industry innovation conference, the founder of the industry in the industry, listened to his views and listened to his views.

Qingyuan Kaiwu was established in 2021, focusing on high-level instruments and equipment and their industrial applications and their industrial applications in 2021. Wang Dong graduated from the Department of Prevision Tools at Tsinghua University and became the head of the BOAO Bio group, the leading local genetic test company. Currently, Qingyuan KaiWU currently has more than 50 employees, mainly focuses on R & D and production groups.

Currently, Qingyuan Kaiwu, pre-processed product lines, mass-spectrometry put several main sectors in a row for pre-processed product lines and synthetic biology. In terms of the product, the company has prepared more than a dozen products, and many of them are about to enter the mass production. “One of our main goals in the future is to draw different directions and allow the implementation of products in more different application scenarios.”

As an example, by taking a product line in advance: the general workflow, the main work of the sequence includes the removal of nucleic acids, splitting nucleic acids and the construction of the NGS library. Given that the development of nucleic acid production in the industry is relatively adult, Qingyuan Kaiwu, product, nucleic acid splitting and NGS library construction is aimed at two main connections.

Currently, well-known methods for the fragmentation of nucleic acids in the industry is the method of cutting the enzyme and ultrasound. Previous, the power of the ultrasound has many advantages such as access to a strong sample, but the cost of tools and consumption materials used is relatively high and is monopolized by foreign companies. For this purpose, the Qingyuan Kaiwu team has been trying to complete the research and development of “internal substitution” for ultrasonic cutting technology and related equipment for two years.

According to reports, there are three advantages of Qingyuan Kaiwu’s ultrasonic cutting technology, which reduces the efficiency of general practice, and this technology is adapted to genome research or this technology can be perfect; Finally, it is above the cost and through innovative technical means, this reduces the sample processing value for the effective way to manage the general value of the generation.

“Unlike external equipment, our ultrasonic cutting does not require special consumers. This can increase the efficiency of all NGS library. This increases the efficiency of the Library construction. According to our estimates, about 1 million yuan for 10,000 samples.

Currently, Qingyuan Kaiwu has collaborated with the NMPA class i registration certificate and CB and CE certificates and third-party test companies in the NMPA class.

In addition, Gingyuan Kaiwu has started a fully automatic gene sequence library preparation system that can achieve the “fully automated process from the exemplary” from sample processing, concentration, concentration, ultrasonic cutting technology.

Wang Dong, based on such a “integrated construction” solution, will simplify the complex process of this gene sequence and thus help in domestic substitution.

In the future, the international market will be the main development of Qingyuan KaiWU. By 2024, the company successfully sold the equipment related to Singapore. In the future, the company will direct to develop European and Southeast Asian markets. “Requirements are relatively easy to maintain products with adult and stable products, in the external and later stages. So far the company’s total external development has become relatively smooth.”



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