(Montreal), cells, mitochondria management of energy power plants in the body circulation in the body can play a key role in the muscle aging, demonstrate the work done in Montreal.
This is an unprecedented mechanism that represents a promising perspective to combat aging-related muscle dysfunctions.
“We can have our finger in the original mechanism of aging, and this is a mechanism that does not slow down with physical activity,” he said.
“We now want to know that we can block (this mechanism) to slow the loss of mass and muscle power accompanying aging.»
Researchers have investigated 139 subjects from 20 to 93 to 93 to 93 years old, or active or inactive.
Active subjects were two good criteria, such as two well-trafficking, such as at least 10,000 steps a day, or at least 150 minutes of medium intensity every week.
The study first confirms that scientific literature is already witnessing: physically better age to remain active.
“We found that people who are active are better functional opportunities, for example, have had better functional opportunities as climbing with chairs or climbing steps,” said Prof.
However, in terms of management, the mitochondry of the calcium in circulation in the body of this work added that this study is in this study.
Researchers have implemented muscular biopsies and then prepared these muscular fibers to the laboratory and the laboratory called “Mitochondrial calcium catchment” in the laboratory. This allowed Mitochondria to gradually observe the detention of calcium.
“With the elderly, mitochondria can handle less and less calcium stress,” Professor Gouspillu.
The results may be important, “The amount of calcium where mitochondria is excessive, it will start a complex mechanism, resulting in muscle atrophy. “The management of calcium by Mitochondria is believed to be dysfunctional with aging.”
If the physical activity is accompanied by numerous benefits, the calcium has not maintained this management of the calcium, the Professor Gaspillou said.
“There are several evidence in the literature, we can increase in the main calcium where mitochondria is always exposed.”
Therefore, the risk of “absolute super positive” combination said: “There is more free calcium in circulation with aging, but the leadership of Mitochondria also has less impact.
If the mitochondria is exposed to Calcium and reached the limit, we are exposed to the risk of professor Gouspillou, muscle atrophy.
“This gradually decreased calcium retention is that the muscle mass, physical performance, muscle strength, and this and this and this and this and this and the parameters are seriously associated with the parameters.
It is something to increase the life of the population, Professor Gouspillu continued, but to allow health, independent and functional to live, it is the important thing.
“Our research is trying to get something interesting in understanding that we are trying to find the muscle mass, muscle power, muscle strength, muscle strength and functional opportunities, so we try to find mobile and molecular mechanisms responsible.
If we successfully determine these mechanisms, he said that maybe we can improve muscle health and target them for the quality of life.
The results of this study were published by the newspaper Cell Drug Drugs.
